The active chemical components of Cannabis are called cannabinoids. There are many different types of cannabinoids in the cannabis plant which have a significant effect on the human body as they possess medicinal properties. Cannabinoids produced by the cannabis plant through its flowers, mimic naturally occurring compounds produced in the human body known as endocannabinoids which maintain and activate internal balance and overall health.
When cannabinoids are consumed, they bind to the most common receptor sites throughout the brain and body known as CB1 and CB2 within the endocannabinoid system (ECS) . The cannabinoid receptors play an important role in communicating changes at the cellular level, and initiating action for the appropriate cellular response.
The CB1 receptor is primarily located in the central nervous system and peripheral nervous system. The CB2 receptor is primarily located in the body, in places such as the immune system.
CBD (cannabidiol) is one of more than 85 chemical compounds found in cannabinoids found in the cannabis plant. CBD is the second most abundant ingredient in the cannabis structure, which usually represents up to 40% of the plant’s extracts.
CBD is non-psychoactive and promotes “relaxation without intoxication.” CBD is believed to have many benefits in healing and promoting health and wellness within the human body. Studies show promise that CBD is a powerful anti-inflammatory, antioxidant, neuroprotectant, anxiolytic (anti-anxiety), antidepressant, analgesic, antiemetic (anti-nausea), and anti-psychotic.
CBDa is the acidic precursor of CBD. CBDa is thought to have both anti-inflammatory and anti-proliferative (inhibits cell growth) traits. Research is currently being done to examine the effects of CBDa on certain types of cancer.
Research on using CBDa for cancer treatment
CBG (Cannabigerol) effects the brain by inhibiting the uptake of GABA, a brain chemical that determines how much stimulation a neuron needs to cause a reaction. When GABA is inhibited it can decrease anxiety and muscle tension.
CBN (Cannabinol) displays similar benefits as CBD such as pain relief and acting as an anti-inflammatory agent. CBN also has powerful sedative properties which in small doses can compare to prescription grade medications for sleep.
THC (Tetrahydrocannabinol) is a psychoactive Cannabinoid found in the Cannabis plant.